Maple Biotech Pvt. Ltd.

Calcium Carboxymethyl Cellulose Powder Manufacturer

Calcium Carboxymethyl Cellulose Powder

Specifications

Purity 99%min
Shelf life 5 Years
Form Powder

Additional Information

Packaging Details As per client requirement

Introduction: Importance of bio-availability and fast disintegration of pharmaceutical tablet is realized and awarness for super-disintegrants in pharmaceutical tablet formulation has also increased. Superdisintegrant viz. Sodium Starch Glycollate was also introduced by Maple Biotech Pvt Ltd. in year 1991, which was appreciated in quality and performance by pharmaceutical industry . Although quest for superior quality superdisintegrant was not over . Superdisintegrant with better stability and superior performance at high tablet hardness level was sought and Maple Biotech's R & D department developed the product Crosslinked Sodium Carboxy Methyl Cellulose which is bearing brand name Cel-Ca-Dissol. Further taking into consideration the requirement for faster dissolution aid for tablets containing ingredients having poor solubility, Calcium Carboxymethylcellulose (Carmellose Calcium) was introduced.

Properties : Carmellose Calcium is white or creamish white in colour and chemically it is Calcium salt of Carboxy Methyl Cellulose with very high degree of purity . Very hard tablets where other superdisintegrants do not perform well Carmellose Calcium performs very much satisfactorily. Quantity to be used in pharmaceutical formulation is very less. Carmellose Calcium helps in dissolution of drugs having poor solubility

Details :

  • Advantages of Carmellose Calcium
  • Fastest dissolution of Drug material
  • good water uptake
  • high capillary action
  • rapid swelling properties
  • efficient fluid channeling
  • compatibility with most actives and excipients
  • excellent long-term stability
  • low usage level
  • low cost-in-use
  • very fast drug dissolution

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Specifications of Carmellose Calcium

Property Specifications
Description White To Yellowish White Hygroscopic Odorless Powder
Identification : Pass A,B,C,D Of Usp,Bp; Ph. Eur
Alkalanity No Pink Colour Developed On Addition Of Phenolpthalein
Moisture Max. 10%
Sulphated Ash @6000 C 10 To 20 % Bp / Ph Eur
Residual Solvent Not More Than 0.05% Usp
Organic Volatile Impurities Usp
Heavy Metals Less Than 20 Ppm Bp, Ph Eur, Usp
Sulphates 1% Bp/ Ph Eur , 0.96% Usp
Chlorides: Less Than 0.5% Bp & Ph Eur/ Less Than 0.36% Usp
Silicates 0.6% Bp/ Ph Eur 1.5% Usp
Starch No Blue Colour With Iodine (USP)
Total Aerobic Microbial Count Less Than 1000 Cfu/Gm
Total Yeast And Mould Count Less Than 100 Cfu/Gm
Pathogens (E.coli, Pseudomonas Aeruginosa,Staphylococcus Aureus Salmonella) Absent





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